Search Icon

Information for researchers

A guide to Research at BWH

This section sets out the procedure and accompanying guidelines for obtaining approval of research projects that are conducted partly or wholly within BWH, or elsewhere by an employee of the Trust. The document is a working overview of the approval process and contains links/references to other relevant documentation and information required by researchers seeking registration of their project.

Guide to research.pdf

Capability Statement

This document outlines the types of studies that the trust are able to Sponsor/Participate in. For further information and general enquiries contact R&[email protected]

Capability statement.pdf Research Passport Application.doc

Key Researchers and Publications

+

Justin Clark – Consultant Obstetrician and Gynaecologist and Honorary Senior Lecturer

Research interests include menstrual disorders, uterine fibroids and polyps, abnormal uterine bleeding, chronic pelvic pain and endometriosis, outpatient ‘office’ gynaecology, hysteroscopy and minimal access surgery.

Cooper NAM, Smith P, Khan KS, Clark TJ. ‘Does cervical preparation before outpatient hysteroscopy reduce patients’ pain experience?’ A systematic review. BJOG 2011;118:1292-301

Clark TJ, Samuels NC, Malick S, Middleton LM, Daniels J, Gupta JK. Bipolar radiofrequency compared with thermal balloon endometrial ablation in the office: a randomized controlled trial. Obstet Gynecol 2011;117:109-18.

Cooper NA, Khan KS, Clark TJ. Local anaesthesia for pain control during outpatient hysteroscopy: systematic review and meta-analysis. BMJ 2010;340:1130

Cooper NAM, Kremer C, Clark TJ. Best Practice in Outpatient Hysteroscopy. Best Practice in Outpatient Hysteroscopy Green Top Guideline 59. RCOG/ BSGE Joint Green Top Guideline. RCOG 2011 www.rcog.org.uk/files/rcog-corp/GTG59Hysteroscopy.pdf

+

Trevor Cole – Consultant in Clinical and Cancer Genetics West Midlands Regional Genetics Service and Honorary Reader in Medical Genetics University of Birmingham

Research interests include endocrine and growth disorders, rare adult and paediatric cancer syndromes and service development in clinical genetics.

Tatton-Bown K, Hanks S, Ruark E, Zachariou A, Duarte Sdel V, Ramsay E, Snape K, Murray A, Perdeaux ER, Seal S, Loveday C, Banka S, Clericuzio C, Flinter F, Magee A, McConnell V, Patton M, Raith W, Rankin J, Splitt M, Strenger V, Taylor C, Wheeler P, Temple KI,  Douglas J, Rahman N, Cole T. Childhood Overgrowth Collaboration. Germline mutations in the oncogene EZH2 cause Weaver syndrome and increased human height. Oncotarget Dec 2011 2 (12) 1127-33.

Daniel PB, Morgan T, Alanay Y, Bijlsma E, Cho T, Cole T, Collins F, David A, Devriendt K, Faivre L, Ikegawa S, Jacquemont S, Jesic M,  Liebrecht D, Marlin S, Morin G, Nishikubo T, Nishimura G, Prescott T, Scarano G, Selicorni A, Shafeghati Y, Skovby F, Tsutsumi S, Whiteford M, Zenker M, Krakow D and Robertson SP. Disease-associated Mutations in the Actin-Binding Domain of Filamin B Cause Cytoplasmic Focal Accumulations Correlating with Disease Severity Human Mutation. 23 Jan 2012 DOI:10.1002/humu.22012

Boyden LM, Choi M, Choate KA, Nelson-Williams CJ, Farhi A, Toka HR, Tikhonova IR, Bjornson R, Mane SM, Colussi G, Lebel M, Gordon RD, Semmekrot BA, Poujol A, Va¨lima¨ki MJ, De Ferrari ME, Sanjad SA, Gutkin M, Karet FE, Tucci JR, Stockigt JR, Keppler-Noreuil KM, Porter CC, Anand SK, Whiteford ML, Davis ID, Dewar SB, Bettinelli A, Fadrowski JJ, Belsha CW, Hunley TE, Nelson RD, Trachtman H, Cole T, Pinsk M, Bockenhauer D, Shenoy M, Vaidyanathan P, Foreman JW,  Rasoulpour M, Thameem F, Al-Shahrouri HZ, Radhakrishnan J, Gharavi AG, Goilav B, Lifton RP. Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature (2012) 482;98-102.

Astuti D, Morris MR, Cooper WN, Staals R, Gentle D, Shuib S, Ricketts CR, Cole T, van Essen AJ, van Lingen R, Neri G, Opitz JM, Rump P, Stolte-Dijkstra I, Pruijn GJM, Latif F, Maher ER. Germline Mutations in DIS3L2 cause the Perlman syndrome of overgrowth and cancer susceptibility. Nature Genetics (2012) doi:10.1038/ng.1071

+

Arri Coomarasamy – Professor of Gynaecology

Research interests include miscarriage and global women’s health.

Wilson A, Gallos ID, Plana N, Lissauer D, Khan KS, Zamora J, MacArthur C, Coomarasamy A. ‘Effectiveness of strategies incorporating training and support of traditional birth attendants on perinatal and maternal mortality’: meta-analysis.  BMJ. 2011 Dec 1;343:d7102. doi: 10.1136/bmj.d7102.

Wilson A, Lissauer D, Thangaratinam S, Khan KS, MacArthur C, Coomarasamy A. ‘A comparison of clinical officers with medical doctors on outcomes of caesarean section in the developing world’: meta-analysis of controlled studies. BMJ. 2011 May 13;342:d2600. doi: 10.1136/bmj.d2600.

Sunkara SK, Rittenberg V, Raine-Fenning N, Bhattacharya S, Zamora J, Coomarasamy A. Association between the number of eggs and live birth in IVF treatment: an analysis of 400 135 treatment cycles. Hum Reprod. 2011 Jul;26(7):1768-74. Epub 2011 May 10.

Thangaratinam S, Tan A, Knox E, Kilby MD, Franklyn J, Coomarasamy A. Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence. BMJ. 2011 May 9;342:d2616. doi: 10.1136/bmj.d2616. Review.

+

Philip Cox – Consultant Perinatal Pathologist

Research interests include the pathology and causation of stillbirth and infant death.

Cox P, Silvestri E, Lazda E, Nash R, Jeffrey I, Ostojic N, Wigglesworth J. Embolism of Brain Tissue in Intrapartum and Early Neonatal Deaths: report of 9 cases. Pediatr Dev Pathol. 2009 Jul 13:1.

Denbow ML, Cox P, Taylor M, Hammal DM, Fisk NM. Placental angioarchitecture in monochorionic twin pregnancies: relationship to fetal growth, feto-fetal transfusion syndrome and pregnancy outcome. American Journal of Obstetrics and Gynecology. 2000: 182; 417-426.

Cox PM, Brueton LA, Bjelogrlic P, Pomroy P, Sewry CA. Diversity of Neuromuscular Pathology in Lethal Multiple Pterygium Syndrome. Pediatr Dev Pathol. 2003 Jan-Feb;6(1):59-68

Meyer E, Ricketts C, Morgan NV, Morris MR, Pasha S, Tee LJ, Rahman F, Bazin A, Bessières B, Déchelotte P, Yacoubi MT, Al-Adnani M, Marton T, Tannahill D, Trembath RC, Fallet-Bianco C, Cox P, Williams D, Maher ER. Mutations in FLVCR2 are associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome (Fowler syndrome). Am J Hum Genet. 2010 Mar 12;86(3):471-8.

+

Jane Daniels- Senior Research Fellow and Deputy Director of the Birmingham Clinical Trials Unit

Research interests include the diagnosis, management and measurement of chronic pelvic pain and heavy menstrual bleeding.

Say L, Chou D, Gemmill A, Tunçalp O, Moller AB, Daniels JP, Gülmezoglu AM, Temmermanm, Alkema L. Global causes of maternal death: a WHO systematic analysis. The Lancet Global Health 2014: 2(6); e323 – e333 2014 doi:10.1016

http://www.ncbi.nlm.nih.gov/pubmed/25103301

Daniels JP, Middleton LJ, Champaneria R, Khan KS, Cooper K, Mol BWJ, Bhattacharya S on behalf of the International Heavy Menstrual Bleeding IPD Meta-analysis Collaborative Group. Second generation endometrial ablation techniques for heavy menstrual bleeding: a network meta-analysis. BMJ 2012;344:e2564

http://www.ncbi.nlm.nih.gov/pubmed/22529302

Daniels J, Gray J, Pattison H, Roberts T, Edwards E, Milner P et al. Rapid testing for GBS during labour: a test accuracy study with evaluation of acceptability and cost-effectiveness. Health Technol Assess 2009;13(42)

http://www.ncbi.nlm.nih.gov/pubmed/19778493

Daniels J, Gray R, Hills RK, Buckley L, Gupta JK, Latthe P, et al on behalf of the LUNA Trial Collaboration. A Randomized Controlled Trial to Assess the Effectiveness of Laparoscopic Uterosacral Nerve Ablation (LUNA) for alleviating Chronic Pelvic Pain. JAMA 2009;302(9):955-961

http://www.ncbi.nlm.nih.gov/pubmed/19724042

+

Andy Ewer – Director of R&D at BWH, Senior Lecturer and Consultant Neonatologist

Research interests include neonatal gastrointestinal function (particularly gastric function and necrotising enterocolitis), neonatal cardiology and clinical trials

Ewer AK, Middleton LJ, Furmston AT, Bhoyar A, Daniels JP, Thangaratinam S, Deeks JJ, Khan KS. Pulse oximetry as a screening test for congenital heart defects in newborn infants (PulseOx): a test accuracy study. Lancet 2011;378:785-94. Epub 2011 Aug 4.

Ewer AK, Furmston AT, Middleton LJ, Deeks JJ, Daniels JP, Pattison HM, Powell R, Roberts TE, Barton P, Auguste P, Bhoyar A, Thangaratinam S, Tonks AM, Satodia P, Deshpande S, Kumaratne B, Sivakumar S, Mupanemunda R,  Khan KS. Pulse oximetry as a screening test for congenital heart defects in newborn infants: a test accuracy study with evaluation of acceptability and cost-effectiveness. Health Technol Assess 2012 (in press).

Thangaratinam S, Brown K, Zamora J, Khan KS, Ewer AK. Pulse oximetry screening for critical congenital heart defects (CCHD) in asymptomatic newborns: A systematic review and meta analysis involving 229 421 babies. Lancet 2012 (in press).

Ewer AK, Al-Salti W, Marshal JM, Coney AM, Ramani P, Booth IW. The role of platelet-activating  factor in a neonatal piglet model of necrotising enterocolitis. Gut 2004;53:207-213.

+

Mike Griffiths – Consultant Clinical Scientist and Director of the West Midlands Regional Genetics Laboratory

Research interests include haemato-oncology genetics, cancer genetics and related stratified medicine projects.

 

Mason J, Akiki S, Griffiths M. Pitfalls in molecular diagnostics in haemato-oncology. Invited editorial review for J Clin Path. 2011;64(4):275-8.

Groves MJ, Sales M, Baker L, Griffiths M, Pratt N, Tauro S. Factors influencing a second myeloid malignancy in patients with Philadelphia negative -7 or del(7q) clones during tyrosine kinase inhibitor therapy of chronic myeloid leukemia. Cancer Genetics and Cytogenetics 2011 Jan;204(1):39-44.

Olavarria E, Siddique S, Griffiths MJ, Avery S, Byrne JL, Piper K, Lennard A, Pallan L, Arrazi K, Perz J, O’Shea D, Goldman J, Apperley JF, Craddock C. Post-transplant Imatinib as a Strategy to Postpone the Requirement for Immunotherapy in Patients Undergoing Reduced Intensity Allografts for Chronic Myeloid Leukemia. Blood 2007; 110(13):4614-4617.

Griffiths M, Mason J, Rindl M, Akiki S, McMullan D, Stinton V, Powell H, Curtis A, Bown N, Craddock C. Acquired isodisomy for chromosome 13 is common in AML, and associated with FLT3-itd mutations. Leukemia. 2005 Dec;19(12):2355-8.

+

Janesh Gupta – Professsor of Obsterics and Gynaecology

Research interests include menorrhagia, chronic pelvic pain, endometriosis and endometrial hyperplasia, including gynaecological minimal access surgery.

Gupta JK, Chien PFW, Voit D, Clark TJ, Khan KS. Ultrasonographic endometrial thickness for diagnosing endometrial pathology in women with postmenopausal bleeding: A meta-analysis. Acta Obstet Gynecol Scand 2002: 81: 799-816.

Varma R, Maher ER, Rollason T, Gupta JK. Endometriosis and the neoplastic process. Reproduction 2004; 127: 293-304.

Clark TJ, Gupta JK. Outpatient thermal balloon ablation of the endometrium. Fertil Steril 2004; 82: 1395-401.

Daniels J, Gray R, Hills RK, Latthe P, Buckley L, Gupta JK, Selman T, Adey E, Xiong T, Champaneria R, Lilford R, Khan KS; LUNA Trial Collaboration. Laparoscopic uterosacral nerve ablation for alleviating chronic pelvic pain: a randomized controlled trial. JAMA 2009; 302(9): 955-61

+

Khalid Ismail – Professor of Obstetrics and Gynaecology

Research interests include the prediction, recognition and management of childbirth-related perineal trauma and the effects of maternal diet and antenatal medications on the fetal epigenome, pregnancy outcomes and susceptibility to disease later on in life.

Kalis V, Laine K, de Leeuw J, Ismail K, Tincello D. Classification of episiotomy: towards a standardisation of terminology. BJOG. 2012 Feb 3. doi: 10.1111/j.1471-0528.2011.03268.x. [Epub ahead of print]

Kettle C, Dowswell T, Ismail KM. Absorbable suture materials for primary repair of episiotomy and second degree tears. Cochrane Database Syst Rev. 2010; (2):CD000006.

Kettle C, Hills R, Ismail KM. Continuous versus interrupted sutures for repair of episiotomy or second degree tears. Cochrane Database Syst Rev. 2007 Oct 17; (4):CD000947.

Nafee T, Farrell, WE, Fryer A, Carroll W, Ismail KM. Epigenetic control of fetal gene expression. BJOG. 2008 Jan; 115(2):158-68.

+

Sara Kenyon – Senior Lecturer in Public Health, Epidemiology and Biostatistics

Research interests include intrapartum care and maternity in women with social risk factors.

Mori R, Tokumasu H, Pledge D, Kenyon S. High dose oxytocin versus low dose oxytocin for augmentation of delayed labour. Cochrane Database of Systematic Reviews, 2011; Issue 10. Arr No CD007201.  DOI:10.1002/14651858.CD007201.pub2.

Kenyon S, Boulvain M, Neilson JP. Antibiotics for preterm rupture of membranes. Cochrane Database of Systematic Reviews, 2010; Issue 8. Art. No.: CD001058. DOI: 10.1002/14651858.CD001058.pub2.

Kenyon S, Pike K, Jones DR, Brocklehurst P, Marlow N, Salt A, Taylor DJ. Childhood outcomes following the prescription of antibiotics to pregnant women with preterm rupture of the membranes: 7 years follow-up of the ORACLE I Trial. Lancet 2008; 372:1310-18.

Kenyon S, Pike K, Jones DR, Brocklehurst P, Marlow N, Salt A, Taylor DJ. Childhood outcomes following the prescription of antibiotics to pregnant women with spontaneous preterm labour: 7 years follow-up of the ORACLE II trial. Lancet 2008; 372:1319-27.

+

Mark Kilby- Professor and Clinical Lead in Fetal Medicine

Research interests include malplacentation and placental pathology, the endocrinology of the fetus and placenta, intrauterine growth restriction, the role of immune tolerance in pregnancy, and treatments in pre-eclampsia.

Slaghekke F, Lopriore E, Lewi L, Middeldorp JM, van Zwet EW, Weingertner AS, Klumper FJ, DeKoninck P, Devlieger R, Kilby MD, Rustico M, Deprest J, Favre R, Oepkes D. Fetoscopic Laser Coagulation of the Vascular Equator versus Selective Coagulation for Twin-to-Twin Transfusion Syndrome: a randomised trial. Lancet.2014; 29(6): 1161-72.

http://www.sciencedirect.com/science/article/pii/S0140673613624198.

Morris RK, Malin GL, Quinlan-Jones E, Middleton LM, Hemming K, Burke D, Daniels JP, Khan KS, Deeks J, Kilby MD. On behalf of the Percutaneous vesicoamniotic shunting in Lower Urinary Tract Obstruction (PLUTO) Collaborative Group.  Percutaneous vesicoamniotic shunting versus conservative management for fetal lower urinary tract obstruction (PLUTO): a randomised trial. Lancet. 2013; 382(9903):1496-506.

http://www.sciencedirect.com/science/article/pii/S0140673613609927.

Morris RK, Riley RD, Doug M, Deeks JJ, Kilby MD. Diagnostic accuracy of spot urinary protein and albumin to creatinine ratios for detection of significant proteinuria or adverse pregnancy outcome in patients with suspected pre-eclampsia: systematic review and meta-analysis. BMJ. 2012;345:e4342.

http://www.bmj.com/content/345/bmj.e4342.long.

Lissauer D, Piper K, Goodyear O, Kilby MD, Moss PA. Fetal-specific CD8+ cytotoxic T cell responses develop during normal human pregnancy and exhibit broad functional capacity. J Immunol. 2012; 189(2): 1072-80.

http://www.jimmunol.org/content/189/2/1072.long.

+

Jackson Kirkman-Brown – Scientific Director of the Assisted Conception Unit at BWH, Senior Lecturer in Human Reproductive Science

Research focus on signalling and regulation of human gametes.

Kirkman-Brown J and Bjõrndahl L. Evaluation of a disposable plastic Neubauer counting chamber for semen analysis. Fertil Steril 2008 Apr 24. PMID: 18439603. JCR (Impact Factor 2009: 3.970, 5yr: 3.961; Eigenfactor Influence Score: 0.931; Rank: 2/26 Reproductive Biology Q1; 3/70 Obstetrics & Gynaecology Q1).

Gadêlha H, Gaffney EA, Smith DJ, Kirkman-Brown JC. Nonlinear instability in flagellar dynamics: a novel modulation mechanism in sperm migration? J R Soc Interface. 2010 Dec 6;7(53):1689 97. PMID: 20462879. JCR (Impact Factor 2009: 4.241, 5yr: 4.466; Eigenfactor Influence Score: 1.760; Rank: 4/50 Multidisciplinary Sciences Q1).

Machado-Oliveira G, Lefièvre L, Ford C, Herrero MB, Barratt CLR, Connolly T, Nash K, Morales-Garcia A, Kirkman-Brown J, Publicover SJ. Mobilisation of Ca2astores and flagellar regulation in human sperm by S-nitrosylation: ‘a role for NO synthesised in the female tract’. Development. 2008. 135, 3677-3686. PMID:18842814. JCR (Impact Factor 2009: 7.194, 5yr: 7.650; Rank: 4/36 Developmental Biology Q1).

Smith DJ, Gaffney EA, Blake JR and Kirkman-Brown JC. Human sperm accumulation near to surfaces: a simulation study. Journal of Fluid Mechanics, Volume 621. 2009, 289-320.  DOI:10.1017/S0022112008004953. JCR (Impact Factor 2009: 2.283, 5yr: 2.698; Eigenfactor Influence Score: 1.380; Rank: 9/123 Mechanics Q1, 10/28 Physics, Fluids & Plasmas Q2).

+

Dr Pallavi Latthe- Consultant Obstetrican and Urogynaecologist

Research interests include systematic reviews and randomised controlled trials in urogynaecology.

Latthe PM, Champaneria R. Dysmenorrhoea. BMJ Clin Evid. Oct 21;2014. pii: 0813.

Bulchandani S, Toozs-Hobson P, Parsons M, McCooty S, Perkins K, Latthe P. Effect of anticholinergics on the overactive bladder and bowel domain of the electronic personal assessment questionnaire (ePAQ). Int Urogynecol J. 2014 Oct 17. [Epub ahead of print]

McCooty S, Latthe P. Electronic pelvic floor assessment questionnaire: a systematic review.

Br J Nurs. 2014 Oct 9;23 Suppl 18: S32-7. doi: 10.12968/bjon.2014.23.Sup18.S32.

Rachaneni S, Latthe P. Does preoperative urodynamics improve outcomes for women undergoing surgery for stress urinary incontinence? A systematic review and meta-analysis. BJOG. 2015 Jan;122(1):8-16. doi: 10.1111/1471-0528.12954. Epub 2014 Jul 15.

+

Christine MacArthur – Professor of Maternal and Child Epidemiology

Research interests include long term childbirth related health problems, such as urinary and faecal incontinence and depression, and the evaluation of maternity health services.

MacArthur C, Glazener C, Lancashire RJ, Herbison P, Wilson D. Exclusive caesarean section delivery and subsequent urinary and faecal incontinence: a twelve year longitudinal study. BJOG 2011. An International Journal of Obstetrics & Gynaecology 118(8):1000-7. DOI 10.1111/j1471-0528.2011.02964.x.

MacArthur C, Jolly K, Ingram L, Freemantle N, Dennis C-L, Hamburger R, Brown J, Chambers J, Khan K. Antenatal peer support workers and breastfeeding initiation: a cluster randomised controlled trial. British Medical Journal 2009; 338:b131. DOI:10.1136/bmj.b131.

MacArthur C, Winter H, Bick D, Knowles H, Lilford R Henderson C, Lancashire R J, Braunholtz, Gee H.  Effects of redesigned community postnatal care on women’s health 4 months after birth: a cluster randomised controlled trial. Lancet 2002; 359:378-385.

MacArthur C, Shennan A, May A, Whyte J, Hickman N, (writing committee) COMET study group. ‘Effect of low-dose mobile versus traditional epidural techniques on mode of delivery’: a randomised controlled trial. Lancet 2011. 358:19-23.

+

Bill Martin – Consultant in Fetal and Maternal Medicine

Research interests include heritability in multiple pregnancy, and preventing preterm labour.

Morris RK, Selman TJ, Harbridge A, Martin WL, Kilby MD. Fetoscopie laser coagulation for severe twin-to-twin transfusion syndrome: factors influencing perinatal outcome, learning cure of the procedure and lessons for new centres. BJOG. 2010 Oct;117(11):1350-7. doi: 10.1111/j.1471-0528.2010.02680.x.

Norman JE, Mackenzie F, Owen P, Mactier H, Hanretty K, Cooper S, Calder A, Mires G, Danielian P, Sturgiss S, MacLennan G, Tydeman G, Thornton S, Martin B, Thornton JG, Neilson JP, Norrie J. Progesterone for the prevention of preterm bith in twin pregnancy (STOPPIT) : a randomised, double-blind, placebo-controlled study and meta-analysis. Lancet. 2009 Jun 13;373(9680):2034-40

Piper KP, McLarnon A, Arrazi J, Horlock C, Ainsworth J, Kilby MD, Martin WL, Moss PA. Functional HY-specific CD8+ T cells are found in a high proportion of women following pregnancy with a male fetus. Biol Reprod. 2007 Jan;76(1):96-101. Epub 2006 Sep 20

 

+

Dominic McMullan – Principal Clinical Scientist, Head of Molecular Cytogenetics

Research focus on the application of whole genome technologies to genetic diagnostics, and the identification of new genes underlying syndromes.

Patel C, Silcock L, McMullan D, Brueton L, Cox H. TBX5 intragenic duplication: a family with an atypical Holt-Oram syndrome phenotype. Eur J Hum Genet. 2012 Feb 15. doi: 10.1038/ejhg.2012.16.

Shuib S, Wei W, Sur H, Morris M, McMullan DJ, Rattenberry E, Meyer E, Maxwell P, Kishida T, Yao m, Latif F, Maher ER. Copy Number Profiling in Von Hippel-Lindau Disease Renal Cell Carcinoma. Genes Chromosomes and Cancer. Genes Chromosomes Cancer. 2011 Jul;50(7):479-88. doi: 10.1002/gcc.20865.

Hillman SC, Pretlove S, Coomarasamy A, McMullan DJ, Davison EV, Maher ER, Kilby MD. Additional information from array comparative genomic hybridization technology over conventional karyotyping in prenatal diagnosis: a systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2011 Jan;37(1):6-14.

McMullan DJ, Bonin M, Hehir-Kwa JY, de Vries BB, Dufke A, Rattenberry E, Steehouwer M, Moruz L, Pfundt R, de Leeuw N, Riess A, Altug-Teber O, Enders H, Singer S, Grasshoff U, Walter M, Walker JM, Lamb CV, Davison EV, Brueton L, Riess O, Veltman JA. Molecular karyotyping of patients with unexplained mental retardation by SNP arrays: a multicenter study. Hum Mutat. 2009 Jul;30(7):1082-92.

+

Philip Moore – Consultant Anaesthetist

Research interests include obstetric anaesthesia.

COMET Study Group UK. Effect of low-dose mobile versus traditional epidural techniques on mode of delivery. Lancet 2001; 358:19-23.

COMET Study Group UK. Randomized Controlled Trial Comparing Traditional with Two “Mobile” Epidural Techniques: Anesthetic and Analgesic Efficacy. Anesthesiology 2002; 97:1567–75

Chilvers J, Geoghegan J, Moore P, Shah J. Internal jugular vein compression to assess the correct placement of an epidural catheter in postpartum women. Anaesthesia 2007; 62: 332–334

Wilson MJ, MacArthur C, Cooper GM, Bick D, Moore PA, Shennan A, COMET Study Group UK. Epidural analgesia and breastfeeding: a randomised controlled trial of epidural techniques with and without fentanyl and a non-epidural comparison group. Anaesthesia 2010; 65:145-53

+

Phil Toozs-Hobson - Lead Urogynaecologist Consultant

Research focus on the changes in the female pelvis due to childbirth.

Obloza A and Toozs-Hobson P. The Current Role of Retropubic Suspensions. Curr Bladder Dysfunct Rep. DOI 10.1007/s11884-014-0275-2. Published online: 30th Jan 2015

Rantell A, Dolan L, Bonner L, Knight S, Ramage C and Toozs-Hobson P. Minimum standards for continence care in the UK.  Neurourology and Urodynamics.  Published online: 16 Jan 2015

Voiding difficulties in the elderly. Philip Toozs-Hobson, Matthew Parsons, Lynne Robinson, Dudley Robinson. Post Reprod Health December 2014 20: 143-147.

Israfil-Bayli F, Toozs-Hobson P, Lees C, Slack M and Ismail K. Cerclage outcome by the type of suture material (COTS): study protocol for a pilot and feasibility randomised controlled trial. Trials 2014, 15:415

+

Sara Webb- Perineal Specialist Midwife

Webb S, Sherburn M, Ismail K. Managing Perineal Trauma after childbirth.  BMJ 2014; 349:g6829

Ahmad A, Webb S, Earley B, Sitch A, Khan K and MacArthur C.  The association between fetal position at the onset of labor and mode of delivery: a prospective cohort study. Accepted manuscript online: 8 Aug 2013 EST| DOI: 10.1002/uog.13189

Webb S, Plana MN, Zamora J, Ahmad A, Earley B, MacCarthur C, Khan K.  Abdominal palpation to determine fetal position at labor onset:  a test accuracy study. Acta Obstetricia et Gynecologica Scandinavica. Vol 90, Issue 11. November 2011, pp 1259–1266.

Webb S, Parsons M. The specialist perineal midwife: making a difference.  MIDIRS Midwiferey Digest, vol 21, no 3, September 2011, pp 351-352